Welcome to the Hashem Lab

Our research is focused on mRNA translation in eukaryotic pathogens and their hosts. We endeavor to understand the regulation of the translation process and decipher structurally, using CryoEM-electron microscopy (cryo-EM), its molecular basis and most importantly, the differences between eukaryotic pathogens and their mammalian hosts.

translation in mammals

mRNA translation in mammals with a particular focus on the structural differences compared to parasites

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translation in parasites

mRNA translation in trypanosomatides and kinetoplastids with a focus on the initiation step and its unique features

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translation in mitochondria

mRNA translation in mitochondria in both pathogenic parasites and their mammalian hosts

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About the lab

We are part of the ARNA unit (Nucleic Acids: Natural and Artificial Regulation),
Inserm U1212 – CNRS UMR 5320 and we are affiliated the University of Bordeaux.
We are located at the European Institute of Chemistry and Biology (IECB) in the city of Bordeaux, France.

Last Tweets

Yaser Hashem
@Hashemyaser4May 12
We are looking to hire new group leader! https://t.co/xJu4JDgmmi
Yaser Hashem
@Hashemyaser4May 11
RT @iecb_bordeaux: Congratulations to our IECB alumni for this prize!
Yaser Hashem
@Hashemyaser4May 11
RT @hauryliuk: I think this might be the biggest discovery by my and @gem__atkinson lab so far: RelA-SpoT Homologue toxins pyrophosphorylat…
Yaser Hashem
@Hashemyaser4May 11
RT @iecb_bordeaux: Congratulations to our group leader and adjunct director @loquet_lab!
Yaser Hashem
@Hashemyaser4May 10
@LugerLab @activemotif Totally love the T-shirts!👏
Yaser Hashem
@Hashemyaser4May 10
@BJ_Greber Reckless-grown-ass adults
Yaser Hashem
@Hashemyaser4May 10
@joachimfrank Absolutely disgusting! Very insulting and cruel to "victims" of all kind
Yaser Hashem
@Hashemyaser4May 07
@loquet_lab @ampere_society @euromar2021 @iecb_bordeaux @BordeauxSts @INC_CNRS @univbordeaux Heyyy congrats Antoine 👏👏👏 well deserved 🥳🥳
Yaser Hashem
@Hashemyaser4May 06
RT @WilsonLab2: Paper coming soon...in the meantime the preprint is available https://t.co/VbpOgtkm4G
Yaser Hashem
@Hashemyaser4May 06
@BobGrassucci Sniff 😢😭 sniff she was like a friend to me 🤓 good bye