Welcome to the Hashem Lab

Our research is focused on mRNA translation in eukaryotic pathogens and their hosts. We endeavor to understand the regulation of the translation process and decipher structurally, using CryoEM-electron microscopy (cryo-EM), its molecular basis and most importantly, the differences between eukaryotic pathogens and their mammalian hosts.

translation in mammals

mRNA translation in mammals with a particular focus on the structural differences compared to parasites

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translation in parasites

mRNA translation in trypanosomatides and kinetoplastids with a focus on the initiation step and its unique features

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translation in mitochondria

mRNA translation in mitochondria in both pathogenic parasites and their mammalian hosts

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About the lab

We are part of the ARNA unit (Nucleic Acids: Natural and Artificial Regulation),
Inserm U1212 – CNRS UMR 5320 and we are affiliated the University of Bordeaux.
We are located at the European Institute of Chemistry and Biology (IECB) in the city of Bordeaux, France.

Last Tweets

Yaser Hashem
@Hashemyaser4Jul 09
RT @ScientistMel: #WearAMask 🤓👇🏻👍 https://t.co/enPhzW37Ck
Yaser Hashem
@Hashemyaser4Jul 08
A must-read for the #amyloid enthusiasts, by the @loquet_lab https://t.co/m6CinGXQIM
Yaser Hashem
@Hashemyaser4Jul 08
RT @a__jomaa: want to know more on how this little guy inhibits translation, read our lastest story on Sars-CoV-2 Nsp1, happy to have been…
Yaser Hashem
@Hashemyaser4Jul 08
RT @The_Ban_Lab: Nsp1 at the end of the tunnel after months of hard work. Congratulations Katharina and Evan @OMuhlemann and @The_Ban_Lab h…
Yaser Hashem
@Hashemyaser4Jul 08
RT @IsraelF96135088: Another structure of SARS-CoV-2/Nsp1 and the 40S (with core eIF3) this time from @The_Ban_Lab in Switzerland
Yaser Hashem
@Hashemyaser4Jul 08
RT @EMDB_EMPIAR: Wow! 🤩 Released @EMDB_EMPIAR & @PDBeurope, & published @IUCrJ, the raw data that led to the beautiful 1.8 Å #CryoEM struct…
Yaser Hashem
@Hashemyaser4Jul 06
RT @SjorsScheres: We've released the first stable version of #RELION-3.1 (3.1.0). 🥳🥳🥳 Download (and use it!) for free from https://t.co/0mp
Yaser Hashem
@Hashemyaser4Jul 05
RT @nature: The fascination with R has turned into unhealthy political and media fixation, say disease experts. https://t.co/Q7aYzGU4C9
Yaser Hashem
@Hashemyaser4Jul 04
RT @gpintilie: A look at the cryoEM maps and RNA models created with the DRRAFTER method https://t.co/xOiDpYbwsP
Yaser Hashem
@Hashemyaser4Jul 03
@fronzes_lab Well... I am not going to "like" you tweet @fronzes_lab, your direction will be sourly missed 😞