Welcome to the Hashem Lab

Our research is focused on mRNA translation in eukaryotic pathogens and their hosts. We endeavor to understand the regulation of the translation process and decipher structurally, using CryoEM-electron microscopy (cryo-EM), its molecular basis and most importantly, the differences between eukaryotic pathogens and their mammalian hosts.

translation in mammals

mRNA translation in mammals with a particular focus on the structural differences compared to parasites

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translation in parasites

mRNA translation in trypanosomatides and kinetoplastids with a focus on the initiation step and its unique features

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translation in mitochondria

mRNA translation in mitochondria in both pathogenic parasites and their mammalian hosts

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About the lab

We are part of the ARNA unit (Nucleic Acids: Natural and Artificial Regulation),
Inserm U1212 – CNRS UMR 5320 and we are affiliated the University of Bordeaux.
We are located at the European Institute of Chemistry and Biology (IECB) in the city of Bordeaux, France.

Last Tweets

Yaser Hashem
@Hashemyaser4Jun 22
@BJ_Greber @IsraelF96135088 Interesting, would you recommend it over the Cryo ARM 300? 🤣🤣 kidding kidding let's not… https://t.co/xjcEKJdd9C
Yaser Hashem
@Hashemyaser4Jun 22
@IsraelF96135088 🤣 BTW what's between the Jamón and the bread?
Yaser Hashem
@Hashemyaser4Jun 22
RT @NatureComms: .@caillancm from @WilsonLab2, @MerianneMohamad, @gem__atkinson, @hauryliuk and colleagues report the structural basis of r…
Yaser Hashem
@Hashemyaser4Jun 22
RT @JohnsHopkinsMBG: Hey Twitterverse, this is Rachel Green, a professor in MBG. Her lab studies how ribosomes work, how protein synthesis…
Yaser Hashem
@Hashemyaser4Jun 22
@adesgeorges @zalk_r @IsraelF96135088 @CNB_CSIC Touchy topic 😅 sorry @IsraelF96135088 didn't want to put you on the spot🙈
Yaser Hashem
@Hashemyaser4Jun 22
@IsraelF96135088 @CNB_CSIC Very very clear 😎
Yaser Hashem
@Hashemyaser4Jun 22
@IsraelF96135088 @CNB_CSIC Would you recommend it over a Titan?
Yaser Hashem
@Hashemyaser4Jun 22
RT @AlexanderSobol6: Happy to share the first full-length structure of glutamate receptor-like channel from plants. Exciting collaboration…
Yaser Hashem
@Hashemyaser4Jun 21
@WilsonLab2 @IgnatovaLab @hauryliuk @gem__atkinson I guess we can all agree now, Vive la résistance !
Yaser Hashem
@Hashemyaser4Jun 21
@IgnatovaLab @WilsonLab2 @hauryliuk @gem__atkinson Heuh how about that! 🤔🤓