Welcome to the Hashem Lab

Our research is focused on mRNA translation in eukaryotic pathogens and their hosts. We endeavor to understand the regulation of the translation process and decipher structurally, using CryoEM-electron microscopy (cryo-EM), its molecular basis and most importantly, the differences between eukaryotic pathogens and their mammalian hosts.

translation in mammals

mRNA translation in mammals with a particular focus on the structural differences compared to parasites

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translation in parasites

mRNA translation in trypanosomatides and kinetoplastids with a focus on the initiation step and its unique features

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translation in mitochondria

mitochondria mRNA translation in unicellular parasites (e.g. Trypanosomes) and hosts (e.g. plants)

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About the lab

We are part of the ARNA unit (Nucleic Acids: Natural and Artificial Regulation),
Inserm U1212 – CNRS UMR 5320 and we are affiliated the University of Bordeaux.
We are located at the European Institute of Chemistry and Biology (IECB) in the city of Bordeaux, France.

Last Tweets

Yaser Hashem
@Hashemyaser4Jun 04
RT @SjorsScheres: This is impressive! We should however be careful in our understanding of what this is. I would argue it is not improving…
Yaser Hashem
@Hashemyaser4Jun 04
RT @oxkawaka: Improvement of cryo-EM maps by simultaneous local and non-local deep learning https://t.co/DOKbgINvZM
Yaser Hashem
@Hashemyaser4May 30
RT @mpi_nat: Congratulations!🥳 We are delighted for @CramerLab 🎉
Yaser Hashem
@Hashemyaser4May 27
Wild life on Technion @TechnionLive campus! Sorry but I must make the joke 🙈 this is not very Kosher 🤣🤓🤣 Surprisin… https://t.co/KbImrtQ7B9
Yaser Hashem
@Hashemyaser4May 25
@zalk_r Hahaha 🤣🤣🤣
Yaser Hashem
@Hashemyaser4May 24
@pmilonma @TechnionLive Hahaha, yes we'll go there too😎
Yaser Hashem
@Hashemyaser4May 24
@pmilonma @TechnionLive If you want à sabbatical in France ... 😎
Yaser Hashem
@Hashemyaser4May 24
@FlorentWaltz 🤣🤣🤣 oh Florent, I'll start searching for the Holy Titan right away
Yaser Hashem
@Hashemyaser4May 24
@yushuv Alright, there might be few gaps in my project plan 😅
Yaser Hashem
@Hashemyaser4May 24
Here's a crazy project; get a Krios titan installed in the Austrian Hospice in Jerusalem, and start a European fund… https://t.co/qSnFO2HYY8