Welcome to the Hashem Lab

Our research is focused on mRNA translation in eukaryotic pathogens and their hosts. We endeavor to understand the regulation of the translation process and decipher structurally, using CryoEM-electron microscopy (cryo-EM), its molecular basis and most importantly, the differences between eukaryotic pathogens and their mammalian hosts.

translation in mammals

mRNA translation in mammals with a particular focus on the structural differences compared to parasites

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translation in parasites

mRNA translation in trypanosomatides and kinetoplastids with a focus on the initiation step and its unique features

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translation in mitochondria

mitochondria mRNA translation in unicellular parasites (e.g. Trypanosomes) and hosts (e.g. plants)

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About the lab

We are part of the ARNA unit (Nucleic Acids: Natural and Artificial Regulation),
Inserm U1212 – CNRS UMR 5320 and we are affiliated the University of Bordeaux.
We are located at the European Institute of Chemistry and Biology (IECB) in the city of Bordeaux, France.

Last Tweets

Yaser Hashem
@Hashemyaser4Mar 20
@Beck_Laboratory @KaczmarekOliver Such a career killer law! We have been suffering in France from a similarly absur… https://t.co/7W5673DnO6
Yaser Hashem
@Hashemyaser4Mar 19
RT @valendraica: I’m excited to share a new manuscript on Sirtuin6-nucleosome structure, a result of a great collaboration between @Peterso
Yaser Hashem
@Hashemyaser4Mar 19
RT @namyolivier: Interested about the diversity of coding genes in yeast? Read our new preprint with amazing colleagues from ⁦@I2BCParisSac
Yaser Hashem
@Hashemyaser4Mar 16
RT @AVBroeck: Pleased to share our latest work where we combined genome editing, biochemistry and cryo-EM to reveal the structural basis fo…
Yaser Hashem
@Hashemyaser4Mar 16
@pmilonma 🤣🤣
Yaser Hashem
@Hashemyaser4Mar 16
RT @ValerieGabelica: Looking forward!
Yaser Hashem
@Hashemyaser4Mar 16
@BaretJc @SynCellEU @CNRSAquitaine @univbordeaux Wawooo 😃 bravo JC 👏 and congrats 🤓
Yaser Hashem
@Hashemyaser4Mar 16
@loquet_lab @iecb_bordeaux @ValerieGabelica @FFriscourt @Guichard_Lab Merci à toi Antoine d'avoir organisé cette visite 🤓👏
Yaser Hashem
@Hashemyaser4Mar 16
@pmilonma 🤣 this how I think of my grant applications when they get funded 🤓🙈