Welcome to the Hashem Lab

Our research is focused on mRNA translation in eukaryotic pathogens and their hosts. We endeavor to understand the regulation of the translation process and decipher structurally, using CryoEM-electron microscopy (cryo-EM), its molecular basis and most importantly, the differences between eukaryotic pathogens and their mammalian hosts.

translation in mammals

mRNA translation in mammals with a particular focus on the structural differences compared to parasites

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translation in parasites

mRNA translation in trypanosomatides and kinetoplastids with a focus on the initiation step and its unique features

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translation in mitochondria

mRNA translation in mitochondria in both pathogenic parasites and their mammalian hosts

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About the lab

We are part of the ARNA unit (Nucleic Acids: Natural and Artificial Regulation),
Inserm U1212 – CNRS UMR 5320 and we are affiliated the University of Bordeaux.
We are located at the European Institute of Chemistry and Biology (IECB) in the city of Bordeaux, France.

Last Tweets

Yaser Hashem
@Hashemyaser4Nov 28
RT @tomcaniels: Getting a call from your PI: "hey, can you make some images detailing the Omicron variant for tonight?" Four hours later,…
Yaser Hashem
@Hashemyaser4Nov 28
RT @BolandLab_GE: 📢 Hi #CryoEM community, we have organised 𝐚 𝟑-𝐝𝐚𝐲𝐬 𝐬𝐲𝐦𝐩𝐨𝐬𝐢𝐮𝐦 with talks in Geneva @unige_en and Lausanne @UNIL @EPFL_en i…
Yaser Hashem
@Hashemyaser4Nov 28
RT @joachimfrank: Sad news: Don Caspar passed away two days ago, at age 94. Rosalind Franklin was one of his mentors. Widely known for his…
Yaser Hashem
@Hashemyaser4Nov 27
RT @N__Fischer: It has been a pleasure to visit @Hashemyaser4 @iecb_bordeaux and meet further members of the vibrant cryo-EM community ther…
Yaser Hashem
@Hashemyaser4Nov 27
@N__Fischer @iecb_bordeaux @fronzes_lab @SisslerM @krastevalab Thank you so much for coming and giving such a fanta… https://t.co/8usUDAeS1w
Yaser Hashem
@Hashemyaser4Nov 27
RT @nevacaliskan: 📢 JOB ALERT: please RT. We are looking for an ambitious and talented postdoc for my @ERC_Research StG project. Join us in…
Yaser Hashem
@Hashemyaser4Nov 25
RT @arna_lab: What a privilege to work with such a passionate scientist! Congratulations Valérie! Well deserved! @ValerieGabelica @Inserm
Yaser Hashem
@Hashemyaser4Nov 25
@LaurentTerradot If I win 160M, I'll retire 🤣
Yaser Hashem
@Hashemyaser4Nov 24
@ValerieGabelica @Fondation_BS Congrats Valérie! Also, very inspiring interview, I really enjoyed it
Yaser Hashem
@Hashemyaser4Nov 24
RT @ericvalmir: Bravo @ValerieGabelica grand prix scientifique 2021 des sciences du vivant. "Ce qui est passionnant dans la recherche est d…