Welcome to the Hashem Lab

Our research is focused on mRNA translation in eukaryotic pathogens and their hosts. We endeavor to understand the regulation of the translation process and decipher structurally, using CryoEM-electron microscopy (cryo-EM), its molecular basis and most importantly, the differences between eukaryotic pathogens and their mammalian hosts.

translation in mammals

mRNA translation in mammals with a particular focus on the structural differences compared to parasites

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translation in parasites

mRNA translation in trypanosomatides and kinetoplastids with a focus on the initiation step and its unique features

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translation in mitochondria

mRNA translation in mitochondria in both pathogenic parasites and their mammalian hosts

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About the lab

We are part of the ARNA unit (Nucleic Acids: Natural and Artificial Regulation),
Inserm U1212 – CNRS UMR 5320 and we are affiliated the University of Bordeaux.
We are located at the European Institute of Chemistry and Biology (IECB) in the city of Bordeaux, France.

Last Tweets

Yaser Hashem
@Hashemyaser4Oct 21
RT @krastevalab: As much as I don't want this, my first PhD student @AbidiWiem flies off the nest soon! If you have a lab in Lausanne or Ge…
Yaser Hashem
@Hashemyaser4Oct 20
RT @EMBOevents: Add your name! Registration now open for the EMBO Workshop on RNA: Structure meets function, 27 June – 1 July 2022 in Åkers…
Yaser Hashem
@Hashemyaser4Oct 20
RT @joachimfrank: Today our team released the long-anticipated ManifoldEM Python (1D beta) suite, available now at https://t.co/08GqysbMPU.
Yaser Hashem
@Hashemyaser4Oct 18
Simply 🤯🤯🤯🤯🤯 https://t.co/hmTNMSeJuo
Yaser Hashem
@Hashemyaser4Oct 18
RT @gonenlab: Density for every amino acid at this resolution below https://t.co/xnuM8xLsTw
Yaser Hashem
@Hashemyaser4Oct 18
@FlorentWaltz Femto-blobology🤓
Yaser Hashem
@Hashemyaser4Oct 16
RT @TrendsBiochem: Online now - a Spotlight from @Ying74382828 @mkrupovic titled "Genome chromatinization in giant double-stranded DNA viru…
Yaser Hashem
@Hashemyaser4Oct 16
@a__jomaa @UVA Wow super exciting, Congrats Ahmad! 👏👏👏
Yaser Hashem
@Hashemyaser4Oct 16
RT @SachseGroup: Members of the Sachse group starring in the current #TerraX @zdf docu (https://t.co/YbC314r6yH) We solved the #CryoEM stru…
Yaser Hashem
@Hashemyaser4Oct 16
ATP-dependent chromatin remodeler, from the @LugerLab https://t.co/ZOkHfrcKd4