Welcome to the Hashem Lab

Our research is focused on mRNA translation in eukaryotic pathogens and their hosts. We endeavor to understand the regulation of the translation process and decipher structurally, using CryoEM-electron microscopy (cryo-EM), its molecular basis and most importantly, the differences between eukaryotic pathogens and their mammalian hosts.

translation in mammals

mRNA translation in mammals with a particular focus on the structural differences compared to parasites

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translation in parasites

mRNA translation in trypanosomatides and kinetoplastids with a focus on the initiation step and its unique features

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translation in mitochondria

mRNA translation in mitochondria in both pathogenic parasites and their mammalian hosts

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About the lab

We are part of the ARNA unit (Nucleic Acids: Natural and Artificial Regulation),
Inserm U1212 – CNRS UMR 5320 and we are affiliated the University of Bordeaux.
We are located at the European Institute of Chemistry and Biology (IECB) in the city of Bordeaux, France.

Last Tweets

Yaser Hashem
@Hashemyaser4Sep 19
RT @buitengebieden_: This runner gave up on gold medal, but proved he has a heart of gold.. https://t.co/b9HK198qCx
Yaser Hashem
@Hashemyaser4Sep 19
RT @CellPressNews: Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4 @molecularcell #cryoem https://t.co/uz4PWCb
Yaser Hashem
@Hashemyaser4Sep 19
RT @Norvey19: The Tundra is looking pretty decent !
Yaser Hashem
@Hashemyaser4Sep 18
RT @ibba_michael: Thanks to my amazing friend and colleague Ignacio Luque - great food led to some great science! https://t.co/eMieDY5XG6
Yaser Hashem
@Hashemyaser4Sep 18
RT @leslievosshall: I am honored and excited to be selected to succeed David Clapham as Vice President and Chief Scientific Officer of the…
Yaser Hashem
@Hashemyaser4Sep 15
RT @Ribomaps: Nice paper showing a heretofore unappreciated role of Not5 on translation elongation and suggests its in a equilibrium with e…
Yaser Hashem
@Hashemyaser4Sep 14
RT @TBharat_lab: We are particularly keen on scientists interested in cryoET method development!
Yaser Hashem
@Hashemyaser4Sep 14
RT @MaierLab: DEPTOR acts as oncogene or tumor suppressor. It is the only protein regulating both #mTOR complexes. In @eLife (https://t.co/
Yaser Hashem
@Hashemyaser4Sep 14
RT @AbhayKot: Another 1.2Å map of Apoferritin #CAFR, now from just 6hrs of data with new Falcon 4i detector. 2 exposures per/hole and data…
Yaser Hashem
@Hashemyaser4Sep 14
RT @TheBlanchardLab: Come join our team at St. Jude Children's Research Hospital! The infrastructure, talent and systems we seek to explore…